Tissue expression
Cell line expression

CAVIN1

gene product
cavin-1, CGL4, PTRF 
This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009]
More gene data

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238 antibodies from 34 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Invitrogen Antibodies
25 antibodies
Novus Biologicals
9 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
21 antibodies
NovoPro Bioscience Inc.
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
antibodies-online
66 antibodies
Boster Biological Technology
2 antibodies
Cell Signaling Technology, Inc
2 antibodies
OriGene
5 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
Aviva Systems Biology
6 antibodies
St John's Laboratory
2 antibodies
ProSci
5 antibodies
Abgent
3 antibodies
Abnova Corporation
7 antibodies
Biorbyt
8 antibodies
Acris Antibodies GmbH
5 antibodies
GeneTex
2 antibodies
Bethyl Laboratories
3 antibodies
Affinity Biosciences
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Diagnostics
7 antibodies
RabMAbs
1 antibody
United States Biological
15 antibodies
MyBioSource
5 antibodies
Creative Biolabs
5 antibodies
EMD Millipore
1 antibody
MilliporeSigma / Merck KGaA
1 antibody
RayBiotech, Inc.
1 antibody
Abbexa
4 antibodies
Rockland Immunochemicals, Inc.
1 antibody