Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
PSMB10
Proteasome 20S subunit beta 10beta2i, LMP10, MECL1, MGC1665
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
| Novus Biologicals |  H00005699-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
|
|
| LSBio | LS-C482445 |
Polyclonal |
WB
ICC
IHC
|
||
| Proteintech Group | 15976-1-AP |
4 references | Polyclonal |
WB
EL
IHC
|
|
| Abnova Corporation | H00005699-M01 |
1 references | Monoclonal |
WB
EL
ICC
|
|
| Invitrogen Antibodies | PA5-19146 |
2 references | Polyclonal |
WB
IHC
OA
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider