Tissue expression
Cell line expression
Protein structure
TDG
Thymine DNA glycosylaseThe protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | 13370-1-AP | 7 references | Polyclonal |
WB
EL
ICC
IP |
|
Invitrogen Antibodies | 13370-1-AP | Polyclonal |
WB
ICC
IP
IHC
ChIP
OA |
||
Novus Biologicals | NBP2-13423 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
GeneTex | GTX110473 | 4 references | Polyclonal |
WB
ICC |
|
antibodies-online | ABIN2840890 | 2 references | Polyclonal |
WB
FC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider