Tissue expression
Cell line expression

CYP7B1

gene product
SPG5A 
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
300 antibodies from 34 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
antibodies-online
101 antibodies
Biorbyt
13 antibodies
Abgent
3 antibodies
LifeSpan BioSciences, Inc.
20 antibodies
NovoPro Bioscience Inc.
4 antibodies
Invitrogen Antibodies
12 antibodies
Aviva Systems Biology
4 antibodies
Novus Biologicals
26 antibodies
Abnova Corporation
6 antibodies
GeneTex
4 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
ProSci
2 antibodies
Cusabio Biotech Co., Ltd
5 antibodies
Boster Biological Technology
2 antibodies
Affinity Biosciences
1 antibody
OriGene
12 antibodies
Acris Antibodies GmbH
3 antibodies
Bioworld Technology, Inc
1 antibody
Antibodies.com
1 antibody
RabMAbs
2 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Creative Diagnostics
5 antibodies
Leading Biology
3 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
MyBioSource
4 antibodies
Abbexa
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
United States Biological
27 antibodies
Creative Biolabs
13 antibodies