CYP7B1

gene product
SPG5A
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
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277 antibodies from 31 providers.

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antibodies-online
101 antibodies
Biorbyt
13 antibodies
Abgent
3 antibodies
NovoPro Bioscience Inc.
4 antibodies
Invitrogen Antibodies
6 antibodies
Aviva Systems Biology
4 antibodies
Novus Biologicals
26 antibodies
LifeSpan BioSciences, Inc.
19 antibodies
Abnova Corporation
6 antibodies
GeneTex
4 antibodies
St John's Laboratory
3 antibodies
ProSci
2 antibodies
Proteintech Group
1 antibody
Affinity Biosciences
1 antibody
OriGene
8 antibodies
Acris Antibodies GmbH
3 antibodies
Bioworld Technology, Inc
1 antibody
Abbexa
1 antibody
Antibodies.com
1 antibody
RabMAbs
2 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Creative Diagnostics
5 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
Creative Biolabs
13 antibodies
MyBioSource
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
United States Biological
27 antibodies
Sigma-Aldrich
2 antibodies