Tissue expression
Cell line expression

DHCR7

gene product
SLOS 
This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2009]
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175 antibodies from 26 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
3 antibodies
Biorbyt
14 antibodies
NSJ Bioreagents
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
Abgent
1 antibody
Acris Antibodies GmbH
1 antibody
Invitrogen Antibodies
6 antibodies
LifeSpan BioSciences, Inc.
37 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
St John's Laboratory
2 antibodies
Aviva Systems Biology
1 antibody
ProSci
1 antibody
antibodies-online
43 antibodies
Atlas Antibodies
1 antibody
Novus Biologicals
3 antibodies
MyBioSource
5 antibodies
Abnova Corporation
2 antibodies
OriGene
1 antibody
United States Biological
13 antibodies
Creative Biolabs
3 antibodies
Leading Biology
3 antibodies
Bethyl Laboratories
1 antibody
Abbexa
3 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Creative Diagnostics
2 antibodies