Tissue expression
Cell line expression
Protein structure
RTKN
RhotekinB5
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | H00006242-M01 | 2 references | Monoclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | MA5-26050 | 1 references | Monoclonal |
WB
IHC
OA
|
|
LSBio | LS-C337804 | Monoclonal |
WB
ICC
IHC
|
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antibodies-online | ABIN393920 | Monoclonal |
WB
EL
IHC
|
||
Acris Antibodies GmbH | AM20937PU-N | Monoclonal |
WB
EL
IHC
|
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