Tissue expression
Cell line expression
Protein structure
PCGF6
Polycomb group ring finger 6MBLR, RNF134
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 10 references | Polyclonal |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Abnova Corporation | Monoclonal |
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| OriGene | 1 references | Polyclonal |
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