ADRB1

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]

Description

adrenoceptor beta 1

Protein family

FDA approved drug targets, G-protein coupled receptors, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Transporters

Chromosome

10:q25.3 (114043866 - 114046904)

Ensembl ID

ENSG00000043591  (ver. 99.38)

Orthologs

Mouse Adrb1: ENSMUSG00000035283

UniProt

P08588

neXtProt

NX_P08588

Human splice variants
Mouse splice variants