RUVBL2

This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008]

Description

RuvB-like AAA ATPase 2

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

19:q13.33 (48993448 - 49015995)

Ensembl ID

ENSG00000183207  (ver. 84.38)

Orthologs

Mouse Ruvbl2: ENSMUSG00000003868

UniProt

Q9Y230

neXtProt

NX_Q9Y230

Human splice variants
Mouse splice variants