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Protein structure
UMPS
Uridine monophosphate synthetaseThis gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Top validated antibodies |
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| Proteintech Group |  14830-1-AP |
5 references | Polyclonal |
WB
EL
IP
IHC
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| Novus Biologicals | H00007372-M05 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | H00007372-M05 |
1 references | Monoclonal |
WB
EL
ICC
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| Atlas Antibodies | HPA036178 |
Polyclonal |
WB
ICC
IHC
|
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| Invitrogen Antibodies | 14830-1-AP |
Polyclonal |
WB
IP
IHC
OA
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