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Cell line expression
Protein structure
CTPS2
CTP synthase 2The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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| LSBio |  LS-C397231 |
Polyclonal |
WB
EL
IP
IHC
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| Proteintech Group | 12852-1-AP |
3 references | Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-113344 |
Polyclonal |
WB
EL
IP
IHC
OA
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| Novus Biologicals | NBP1-86055 |
1 references | Polyclonal |
WB
ICC
IHC
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| Atlas Antibodies | HPA017437 |
1 references | Polyclonal |
WB
ICC
IHC
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