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Protein structure
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  17838-1-AP |
5 references | Polyclonal |
WB
EL
IHC
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| Biorbyt | orb745960 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | NBP1-45238 |
1 references | Polyclonal |
WB
EL
IHC
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| Boster Biological Technology | A05977 |
Polyclonal |
WB
EL
ICC
FC
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| Abgent | AP8146a |
3 references | Polyclonal |
WB
IHC
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