Tissue expression
Cell line expression
Protein structure
JAK3
Janus kinase 3JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ABIN2869455 | 3 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Invitrogen Antibodies | MA5-15561 | 1 references | Monoclonal |
WB
EL
ICC
FC
OA
|
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Novus Biologicals | NBP2-37737 | 1 references | Monoclonal |
WB
EL
ICC
FC |
|
OriGene | AM06376SU-N | Monoclonal |
WB
EL
ICC
FC |
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GeneTex | GTX83303 | Monoclonal |
WB
EL
ICC
FC |
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Supportive data in Antibodypedia
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Recommended by provider