JAK3
gene productJAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Featured antibodies
 Biorbyt |
 orb69195 |
0 references | Monoclonal |
WB
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IHC
FC
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 Sigma-Aldrich |
J3752 |
0 references | Polyclonal |
IP
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