ABI1

gene product
ABI-1, E3B1, SSH3BP1
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
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315 antibodies from 35 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
116 antibodies
NSJ Bioreagents
3 antibodies
OriGene
5 antibodies
GeneTex
3 antibodies
Abnova Corporation
4 antibodies
Abgent
1 antibody
Boster Biological Technology
2 antibodies
Invitrogen Antibodies
4 antibodies
Aviva Systems Biology
6 antibodies
Acris Antibodies GmbH
6 antibodies
Biorbyt
15 antibodies
ProSci
1 antibody
LifeSpan BioSciences, Inc.
68 antibodies
Bethyl Laboratories
4 antibodies
Novus Biologicals
5 antibodies
Atlas Antibodies
2 antibodies
Affinity Biosciences
2 antibodies
RabMAbs
2 antibodies
Cell Signaling Technology, Inc
1 antibody
MyBioSource
9 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Abbiotec
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
Creative Biolabs
1 antibody
Creative Diagnostics
1 antibody
EMD Millipore
4 antibodies
Abiocode, Inc.
1 antibody
BioLegend (formerly Covance Antibody Products)
1 antibody
GenWay
1 antibody
NovoPro Bioscience Inc.
1 antibody
St John's Laboratory
1 antibody
United States Biological
26 antibodies
Sigma-Aldrich
2 antibodies