Tissue expression
Cell line expression
Protein structure
TYR
TyrosinaseOCA1, OCA1A, OCAIA
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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Invitrogen Antibodies | MA5-14177 | 29 references | Monoclonal |
WB
ICC
IHC
OA |
|
antibodies-online | ABIN453446 | 2 references | Polyclonal |
WB
ICC
IHC
FC |
|
NSJ Bioreagents | V2290 | 9 references | Monoclonal |
WB
ICC
IHC
FC
OA
|
|
Novus Biologicals | NBP2-34770-0.1 mg | Monoclonal |
WB
EL
ICC
IP
IHC
FC |
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OriGene | AM32831PU-S | Monoclonal |
WB
ICC
IP
IHC
FC
|
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Supportive data in Antibodypedia
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Recommended by provider