PAX5

gene product
BSAP
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
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829 antibodies from 44 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
14 antibodies
antibodies-online
303 antibodies
Novus Biologicals
81 antibodies
GeneTex
11 antibodies
NSJ Bioreagents
8 antibodies
Biorbyt
31 antibodies
LifeSpan BioSciences, Inc.
76 antibodies
OriGene
63 antibodies
Acris Antibodies GmbH
16 antibodies
Cell Signaling Technology, Inc
4 antibodies
R&D Systems
10 antibodies
Abgent
8 antibodies
Boster Biological Technology
2 antibodies
Abnova Corporation
13 antibodies
NovoPro Bioscience Inc.
9 antibodies
Aviva Systems Biology
5 antibodies
Affinity Biosciences
2 antibodies
Atlas Antibodies
2 antibodies
ProSci
5 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
BioLegend
11 antibodies
RabMAbs
4 antibodies
Antibodies.com
1 antibody
Arigo
5 antibodies
Proteintech Group
2 antibodies
Everest Biotech
1 antibody
ABEOMICS Inc.
2 antibodies
United States Biological
55 antibodies
Creative Diagnostics
5 antibodies
FabGennix
9 antibodies
MyBioSource
12 antibodies
Bioworld Technology, Inc
1 antibody
Signalway Antibody LLC
1 antibody
Miltenyi Biotec
8 antibodies
Spring Bioscience
8 antibodies
St John's Laboratory
6 antibodies
Abiocode, Inc.
1 antibody
RayBiotech, Inc.
1 antibody
EMD Millipore
3 antibodies
eBioscience, An Affymetrix Company
6 antibodies
GenWay
4 antibodies
Sigma-Aldrich
2 antibodies
Nordic BioSite
4 antibodies