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Protein structure
MYBPC3
Myosin binding protein C3CMH4, cMyBP-C, FHC
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  19977-1-AP |
3 references | Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C164695 |
Polyclonal |
WB
IHC
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| antibodies-online | ABIN953556 |
5 references | Polyclonal |
WB
IHC
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| Enzo Life Sciences | ALX-215-057-R050 |
2 references | Polyclonal |
WB
ICC
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| Biorbyt | orb2613 |
Polyclonal |
WB
EL
ICC
IHC
|
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