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Protein structure
CCDC22
Coiled-coil domain containing 22CXorf37, JM1
This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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| Proteintech Group |  16636-1-AP |
17 references | Polyclonal |
WB
EL
IP
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| Novus Biologicals | NBP1-84331 |
1 references | Polyclonal |
WB
ICC
IHC
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| GeneTex | GTX32079 |
Polyclonal |
WB
EL
ICC
IHC
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| Atlas Antibodies | HPA000888 |
1 references | Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C810098 |
Polyclonal |
WB
EL
IHC
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