Tissue expression
Cell line expression
Protein structure
PLCB1
Phospholipase C beta 1KIAA0581, PLC-I, PLC154
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Proteintech Group | 5 references | Polyclonal |
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| antibodies-online | 3 references | Polyclonal |
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| Santa Cruz Biotechnology | 2 references | Polyclonal (Antigen purified) |
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| GeneTex | Polyclonal |
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