Tissue expression
Cell line expression
Protein structure
PDGFA
Platelet derived growth factor subunit APDGF-A, PDGF1
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Top validated antibodies |
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| R&D Systems | 6 references | Polyclonal |
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| Novus Biologicals | 6 references | Polyclonal |
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| LSBio | Polyclonal |
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| antibodies-online | 2 references | Polyclonal |
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| GeneTex | Polyclonal |
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