TBP

gene product
GTF2D1, SCA17, TFIID
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]
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527 antibodies from 38 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
9 antibodies
antibodies-online
194 antibodies
NSJ Bioreagents
9 antibodies
Abgent
6 antibodies
OriGene
10 antibodies
Santa Cruz Biotechnology
1 antibody
NovoPro Bioscience Inc.
7 antibodies
GeneTex
12 antibodies
St John's Laboratory
9 antibodies
Proteintech Group
3 antibodies
ProSci
5 antibodies
LifeSpan BioSciences, Inc.
50 antibodies
Affinity Biosciences
3 antibodies
Cell Signaling Technology, Inc
4 antibodies
Aviva Systems Biology
5 antibodies
Biorbyt
38 antibodies
Novus Biologicals
4 antibodies
Abnova Corporation
7 antibodies
Creative Diagnostics
16 antibodies
Boster Biological Technology
4 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
2 antibodies
Signalway Antibody LLC
1 antibody
Abbkine Scientific Co.Ltd.
6 antibodies
Antibodies.com
2 antibodies
Abbexa
6 antibodies
Bethyl Laboratories
1 antibody
Acris Antibodies GmbH
6 antibodies
Everest Biotech
2 antibodies
MyBioSource
13 antibodies
Arigo
1 antibody
RabMAbs
3 antibodies
Active Motif
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
United States Biological
76 antibodies
EMD Millipore
2 antibodies
GenWay
5 antibodies
Sigma-Aldrich
2 antibodies