SPTBN2

gene product
SCA5
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
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615 antibodies from 21 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
151 antibodies
NSJ Bioreagents
11 antibodies
antibodies-online
358 antibodies
Invitrogen Antibodies
7 antibodies
Atlas Antibodies
2 antibodies
R&D Systems
1 antibody
Santa Cruz Biotechnology
1 antibody
Biorbyt
18 antibodies
LifeSpan BioSciences, Inc.
36 antibodies
Proteintech Group
1 antibody
Abnova Corporation
12 antibodies
ABEOMICS Inc.
2 antibodies
OriGene
2 antibodies
GeneTex
5 antibodies
Bethyl Laboratories
2 antibodies
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
1 antibody
Creative Diagnostics
1 antibody
EMD Millipore
1 antibody
Sigma-Aldrich
1 antibody
United States Biological
1 antibody