Tissue expression
Cell line expression
Protein structure
PRPF8
Pre-mRNA processing factor 8hPrp8, Prp8, PRPC8, RP13, SNRNP220
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 9 references | Polyclonal |
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| Invitrogen Antibodies | Monoclonal |
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| Novus Biologicals | Monoclonal |
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| Boster Biological Technology | Polyclonal |
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| antibodies-online | Polyclonal |
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