Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
IL2
Interleukin 2IL-2, TCGF
This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Sep 2020]
Top validated antibodies |
|||||
| R&D Systems |  AF-502-NA |
5 references | Polyclonal |
WB
EL
ICC
IHC
BN
|
|
| Novus Biologicals | AF-502-NA |
5 references | Polyclonal |
WB
ICC
IHC
BN
|
|
| Invitrogen Antibodies | 701080 |
1 references | Monoclonal |
WB
IHC
FC
OA
|
|
| Proteintech Group | 60306-1-Ig |
4 references | Monoclonal |
WB
EL
ICC
IHC
|
|
| antibodies-online | ABIN2869388 |
2 references | Monoclonal |
WB
EL
ICC
IHC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider