TNPO1

This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. [provided by RefSeq, Jul 2008]

Description

transportin 1

Protein family

Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

5:q13.2 (72816312 - 72916733)

Ensembl ID

ENSG00000083312  (ver. 84.38)

Orthologs

Mouse Tnpo1: ENSMUSG00000009470

UniProt

Q92973

neXtProt

NX_Q92973

Human splice variants
Mouse splice variants