CTSW

The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008]

Description

cathepsin W

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted secreted proteins, Protein evidence (Peptideatlas)

Chromosome

11:q13.1 (65879837 - 65883741)

Ensembl ID

ENSG00000172543  (ver. 99.38)

Orthologs

Mouse Ctsw: ENSMUSG00000024910

UniProt

P56202

neXtProt

NX_P56202

Human splice variants
Mouse splice variants