TCF3

gene product
bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, VDIR
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]
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533 antibodies from 42 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
28 antibodies
Atlas Antibodies
2 antibodies
Santa Cruz Biotechnology
1 antibody
GeneTex
8 antibodies
antibodies-online
189 antibodies
Abnova Corporation
7 antibodies
Biorbyt
30 antibodies
NovoPro Bioscience Inc.
6 antibodies
LifeSpan BioSciences, Inc.
73 antibodies
Aviva Systems Biology
9 antibodies
Abgent
5 antibodies
OriGene
13 antibodies
R&D Systems
4 antibodies
Invitrogen Antibodies
6 antibodies
Acris Antibodies GmbH
9 antibodies
Affinity Biosciences
2 antibodies
Antibodies.com
2 antibodies
Arigo
2 antibodies
St John's Laboratory
7 antibodies
ProSci
5 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
BioLegend
1 antibody
Bioworld Technology, Inc
1 antibody
Cell Signaling Technology, Inc
2 antibodies
Boster Biological Technology
1 antibody
Proteintech Group
1 antibody
Abbkine Scientific Co.Ltd.
3 antibodies
Creative Biolabs
18 antibodies
EMD Millipore
1 antibody
United States Biological
50 antibodies
Abiocode, Inc.
3 antibodies
MyBioSource
7 antibodies
Abbiotec
2 antibodies
RayBiotech, Inc.
2 antibodies
Creative Diagnostics
3 antibodies
Bethyl Laboratories
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
GenWay
5 antibodies
Abbexa
4 antibodies
Sigma-Aldrich
5 antibodies