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Cell line expression
Protein structure
MAPK7
Mitogen-activated protein kinase 7BMK1, ERK5, PRKM7
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  BSM-52069R |
Monoclonal |
WB
ICC
IHC
FC
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| LSBio | LS-C331904 |
Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | NBP2-67802 |
Monoclonal |
WB
ICC
IP
FC
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| Proteintech Group | 10036-2-AP |
4 references | Polyclonal |
WB
EL
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| Boster Biological Technology | A02812-1 |
Polyclonal |
WB
ICC
IP
FC
|
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