Tissue expression
Cell line expression
Protein structure

CSTB

Cystatin B
CST6, EPM1, PME, STFB 
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies. [provided by RefSeq, Jul 2016]
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857 antibodies from 38 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
43 antibodies
Proteintech Group
2 antibodies
NovoPro Bioscience Inc.
1 antibody
OriGene
27 antibodies
Novus Biologicals
8 antibodies
R&D Systems
5 antibodies
Boster Biological Technology
6 antibodies
Atlas Antibodies
2 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
antibodies-online
243 antibodies
Acris Antibodies GmbH
10 antibodies
Aviva Systems Biology
6 antibodies
Biorbyt
49 antibodies
Abnova Corporation
11 antibodies
NSJ Bioreagents
5 antibodies
Affinity Biosciences
1 antibody
St John's Laboratory
5 antibodies
Bioworld Technology, Inc
1 antibody
Everest Biotech
1 antibody
Abgent
9 antibodies
GeneTex
9 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
ProSci
5 antibodies
Creative Diagnostics
6 antibodies
Antibodies.com
1 antibody
RabMAbs
4 antibodies
MilliporeSigma / Merck KGaA
6 antibodies
MyBioSource
17 antibodies
Abbexa
13 antibodies
RayBiotech, Inc.
4 antibodies
Arigo
1 antibody
United States Biological
95 antibodies
Leading Biology
8 antibodies
Creative Biolabs
59 antibodies
CPTAC
3 antibodies