SVIL

gene product
This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Jul 2008]
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107 antibodies from 18 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
4 antibodies
Atlas Antibodies
2 antibodies
antibodies-online
39 antibodies
Invitrogen Antibodies
2 antibodies
Abgent
1 antibody
NovoPro Bioscience Inc.
1 antibody
LifeSpan BioSciences, Inc.
25 antibodies
Abnova Corporation
2 antibodies
Biorbyt
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
MyBioSource
1 antibody
R&D Systems
1 antibody
Creative Biolabs
4 antibodies
Sigma-Aldrich
4 antibodies
Creative Diagnostics
1 antibody
St John's Laboratory
1 antibody
United States Biological
1 antibody