Tissue expression
Cell line expression
Protein structure
GABRA1
Gamma-aminobutyric acid type A receptor subunit alpha1EJM5
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 33 references | Polyclonal |
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| LSBio | Monoclonal |
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| Novus Biologicals | 11 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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