Tissue expression
Cell line expression
Protein structure
RNF213
Ring finger protein 213ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57
This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Top validated antibodies |
|||||
Invitrogen Antibodies | PA5-51902 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Novus Biologicals | NBP1-88466 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
antibodies-online | ABIN2035203 | Polyclonal |
WB
EL
IHC
FC |
||
Atlas Antibodies | HPA003347 | Polyclonal |
WB
ICC
IHC
|
||
Abnova Corporation | PAB29398 | Polyclonal |
WB
ICC
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider