JAM2

This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]

Description

junctional adhesion molecule 2

Protein family

CD markers, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

21:q21.3 (25639272 - 25717562)

Ensembl ID

ENSG00000154721  (ver. 84.38)

Orthologs

Mouse Jam2: ENSMUSG00000053062

UniProt

P57087

neXtProt

NX_P57087

Human splice variants
Mouse splice variants