Tissue expression
Cell line expression
Protein structure
ABI3
ABI family member 3NESH, SSH3BP3
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Top validated antibodies |
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| LSBio | Polyclonal |
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| GeneTex | Polyclonal |
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| antibodies-online | Polyclonal |
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| Acris Antibodies GmbH | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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