Tissue expression
Cell line expression
Protein structure
TRIB3
Tribbles pseudokinase 3C20orf97, dJ1103G7.3, TRB3
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
Top validated antibodies |
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GeneTex | GTX113991 | 2 references | Polyclonal |
WB
ICC
IHC
|
|
Proteintech Group | 13300-1-AP | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Invitrogen Antibodies | H00057761-M06 | Monoclonal |
WB
EL
ICC
OA |
||
antibodies-online | ABIN393625 | Monoclonal |
WB
EL
ICC
IHC |
||
Novus Biologicals | H00057761-M03 | Monoclonal |
WB
EL
ICC
BN |
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