TPM1

gene product
C15orf13, CMH3
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
290 antibodies from 34 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
antibodies-online
93 antibodies
GeneTex
7 antibodies
Biorbyt
6 antibodies
Atlas Antibodies
2 antibodies
Abnova Corporation
3 antibodies
Bioworld Technology, Inc
2 antibodies
LifeSpan BioSciences, Inc.
36 antibodies
Invitrogen Antibodies
4 antibodies
Affinity Biosciences
1 antibody
OriGene
11 antibodies
Acris Antibodies GmbH
9 antibodies
Aviva Systems Biology
3 antibodies
Santa Cruz Biotechnology
1 antibody
RabMAbs
5 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
St John's Laboratory
3 antibodies
Boster Biological Technology
4 antibodies
ProSci
3 antibodies
NovoPro Bioscience Inc.
1 antibody
Creative Diagnostics
9 antibodies
United States Biological
37 antibodies
Cell Signaling Technology, Inc
2 antibodies
MyBioSource
6 antibodies
Sigma-Aldrich
5 antibodies
Creative Biolabs
1 antibody
EMD Millipore
4 antibodies
GenWay
4 antibodies
NSJ Bioreagents
3 antibodies
Abgent
1 antibody
Arigo
1 antibody
RayBiotech, Inc.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody