COL25A1

gene product
This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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164 antibodies from 22 providers.

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antibodies-online
63 antibodies
Acris Antibodies GmbH
5 antibodies
Affinity Biosciences
1 antibody
Novus Biologicals
8 antibodies
OriGene
3 antibodies
GeneTex
3 antibodies
Biorbyt
9 antibodies
Invitrogen Antibodies
4 antibodies
LifeSpan BioSciences, Inc.
29 antibodies
Abnova Corporation
4 antibodies
Aviva Systems Biology
2 antibodies
RabMAbs
1 antibody
Abbkine Scientific Co.Ltd.
2 antibodies
R&D Systems
2 antibodies
St John's Laboratory
2 antibodies
Boster Biological Technology
1 antibody
Creative Biolabs
9 antibodies
Creative Diagnostics
3 antibodies
GenWay
2 antibodies
Sigma-Aldrich
3 antibodies
United States Biological
6 antibodies
MyBioSource
2 antibodies