UBE2D2

gene product
UBC4, UbcH5B
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
344 antibodies from 27 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
123 antibodies
Novus Biologicals
27 antibodies
LifeSpan BioSciences, Inc.
55 antibodies
OriGene
20 antibodies
Acris Antibodies GmbH
4 antibodies
Abnova Corporation
3 antibodies
Atlas Antibodies
1 antibody
Abgent
4 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
5 antibodies
Invitrogen Antibodies
5 antibodies
Biorbyt
18 antibodies
ProSci
3 antibodies
Boster Biological Technology
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
GeneTex
1 antibody
Creative Diagnostics
7 antibodies
St John's Laboratory
2 antibodies
Creative Biolabs
9 antibodies
MyBioSource
5 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
27 antibodies
Sigma-Aldrich
3 antibodies
RabMAbs
2 antibodies
GenWay
1 antibody