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Protein structure
WWOX
WW domain containing oxidoreductaseFOR, SDR41C1, WOX1
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-29701 |
3 references | Polyclonal |
WB
ICC
IHC
OA
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| Proteintech Group | 15299-1-AP |
4 references | Polyclonal |
WB
EL
IP
IHC
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| Boster Biological Technology | A01223-1 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| antibodies-online | ABIN556377 |
Polyclonal |
WB
ICC
IP
IHC
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| GeneTex | GTX113325 |
Polyclonal |
WB
ICC
IP
IHC
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