Tissue expression
Cell line expression
Protein structure

CTSS

Cathepsin S
 
The preproprotein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that participates in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The mature protein cleaves the invariant chain of MHC class II molecules in endolysosomal compartments and enables the formation of antigen-MHC class II complexes and the proper display of extracellular antigenic peptides by MHC-II. The mature protein also functions as an elastase over a broad pH range. When secreted from cells, this protein can remodel components of the extracellular matrix such as elastin, collagen, and fibronectin. This gene is implicated in the pathology of many inflammatory and autoimmune diseases and, given its elastase activity, plays a significant role in some pulmonary diseases. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2020]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
516 antibodies from 37 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
3 antibodies
Atlas Antibodies
1 antibody
Novus Biologicals
50 antibodies
GeneTex
3 antibodies
antibodies-online
140 antibodies
Invitrogen Antibodies
8 antibodies
OriGene
8 antibodies
Abnova Corporation
8 antibodies
Abgent
5 antibodies
Biorbyt
49 antibodies
Aviva Systems Biology
4 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
Boster Biological Technology
3 antibodies
Affinity Biosciences
1 antibody
St John's Laboratory
6 antibodies
ProSci
1 antibody
Signalway Antibody LLC
1 antibody
Acris Antibodies GmbH
11 antibodies
NovoPro Bioscience Inc.
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
Absolute Antibody
4 antibodies
RabMAbs
3 antibodies
Creative Diagnostics
8 antibodies
Arigo
1 antibody
MyBioSource
11 antibodies
Leading Biology
5 antibodies
United States Biological
19 antibodies
Abbexa
9 antibodies
RayBiotech, Inc.
3 antibodies
Cell Signaling Technology, Inc
1 antibody
Proteintech Group
1 antibody
Creative Biolabs
36 antibodies
EMD Millipore
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies