MAPRE2

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Description

microtubule associated protein RP/EB family member 2

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

18 (34976928 - 35143470)

Ensembl ID

ENSG00000166974  (ver. 98.38)

Orthologs

Mouse Mapre2: ENSMUSG00000024277

UniProt

Q15555

neXtProt

NX_Q15555

Human splice variants
Mouse splice variants