Tissue expression
Cell line expression
Protein structure

F13B

Coagulation factor XIII B chain
FXIIIB 
This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008]
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266 antibodies from 25 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
44 antibodies
Biorbyt
32 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
Atlas Antibodies
2 antibodies
GeneTex
1 antibody
St John's Laboratory
3 antibodies
antibodies-online
48 antibodies
Aviva Systems Biology
4 antibodies
Invitrogen Antibodies
17 antibodies
OriGene
11 antibodies
Abnova Corporation
1 antibody
Abbkine Scientific Co.Ltd.
2 antibodies
Boster Biological Technology
1 antibody
Affinity Biosciences
1 antibody
MyBioSource
4 antibodies
Abbexa
3 antibodies
ProSci
2 antibodies
Creative Diagnostics
6 antibodies
Green Mountain Antibodies
1 antibody
United States Biological
13 antibodies
Creative Biolabs
9 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Leading Biology
1 antibody
Sino Biological Inc.
1 antibody