Tissue expression
Cell line expression

F13B

gene product
FXIIIB 
This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
243 antibodies from 25 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
44 antibodies
Atlas Antibodies
2 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
LifeSpan BioSciences, Inc.
51 antibodies
GeneTex
1 antibody
St John's Laboratory
3 antibodies
antibodies-online
48 antibodies
Aviva Systems Biology
4 antibodies
Invitrogen Antibodies
12 antibodies
Biorbyt
14 antibodies
OriGene
11 antibodies
Abnova Corporation
1 antibody
Abbkine Scientific Co.Ltd.
2 antibodies
Boster Biological Technology
1 antibody
Affinity Biosciences
1 antibody
MyBioSource
4 antibodies
Abbexa
3 antibodies
ProSci
2 antibodies
Creative Diagnostics
6 antibodies
Green Mountain Antibodies
1 antibody
United States Biological
13 antibodies
Creative Biolabs
9 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Leading Biology
1 antibody
Sino Biological Inc.
1 antibody