Tissue expression
Cell line expression

ADORA2A

gene product
ADORA2, RDC8 
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
455 antibodies from 41 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
50 antibodies
Invitrogen Antibodies
11 antibodies
LifeSpan BioSciences, Inc.
71 antibodies
OriGene
9 antibodies
Aviva Systems Biology
8 antibodies
Affinity Biosciences
3 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Biorbyt
40 antibodies
Boster Biological Technology
3 antibodies
Acris Antibodies GmbH
6 antibodies
Bioworld Technology, Inc
3 antibodies
Proteintech Group
2 antibodies
antibodies-online
35 antibodies
Enzo Life Sciences
2 antibodies
St John's Laboratory
4 antibodies
Abgent
4 antibodies
Antibodies.com
1 antibody
Arigo
1 antibody
Cell Signaling Technology, Inc
1 antibody
Everest Biotech
1 antibody
ProSci
3 antibodies
R&D Systems
17 antibodies
Creative Biolabs
24 antibodies
Abbexa
10 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Atlas Antibodies
1 antibody
United States Biological
75 antibodies
MyBioSource
9 antibodies
Creative Diagnostics
8 antibodies
EMD Millipore
3 antibodies
Signalway Antibody LLC
2 antibodies
Leading Biology
5 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
SICGEN
1 antibody
Absolute Antibody
5 antibodies
RayBiotech, Inc.
2 antibodies
GenWay
1 antibody
NSJ Bioreagents
1 antibody
Abnova Corporation
1 antibody
RabMAbs
1 antibody