Tissue expression
Cell line expression
Protein structure
STC1
Stanniocalcin 1STC
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 13 references | Polyclonal |
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| OriGene | 2 references | Monoclonal |
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| Novus Biologicals | 1 references | Monoclonal |
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| antibodies-online | 4 references | Polyclonal |
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| Abbexa | Polyclonal |
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