SIRT3

Sirtuin 3

SIR2L3

SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]

Ensembl	UniProt	RefSeq	Entrez
ENST00000382743 ENSP00000372191	Q9NTG7.174 Q9NTG7	NP_036371.1 NP_036371 NP_001357239.1 NP_001357239	SIRT3 23410
ENST00000524564 ENSP00000432937	E9PN58	NP_001357241.1 NP_001357241	SIRT3 23410
ENST00000525237 ENSP00000436085	E9PR48		SIRT3 23410
ENST00000525319 ENSP00000435464	E9PK80	NP_001357244.1 NP_001357244	SIRT3 23410
ENST00000525776 ENSP00000433132	E9PM52		SIRT3 23410
ENST00000528469 ENSP00000432857	E9PNA0		SIRT3 23410
ENST00000529382 ENSP00000437216	Q9NTG7.174 Q9NTG7	NP_001357249.1 NP_001357249 NP_001357248.1 NP_001357248 NP_001357247.1 NP_001357247 NP_001017524.1 NP_001017524 NP_001357251.1 NP_001357251 NP_001357252.1 NP_001357252 NP_001357250.1 NP_001357250 NP_001357254.1 NP_001357254 NP_001357253.1 NP_001357253	SIRT3 23410
ENST00000532956 ENSP00000433077	E9PM75	NP_001357243.1 NP_001357243	SIRT3 23410

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000026559 ENSMUSP00000026559	Q8R104.156 Q8R104 Q4FJK3	NP_071878.2 NP_071878	Sirt3 64384
ENSMUST00000106048 ENSMUSP00000101663	Q8R104.156 Q8R104 Q4FJK3	NP_001120823.1 NP_001120823 NP_001171275.1 NP_001171275	Sirt3 64384
ENSMUST00000137024 ENSMUSP00000114247	D3YVQ5		Sirt3 64384
ENSMUST00000137710 ENSMUSP00000115202	D3YWD6		Sirt3 64384
ENSMUST00000147331 ENSMUSP00000121151	D3YTK6		Sirt3 64384
ENSMUST00000210296 ENSMUSP00000147504	A0A1B0GRF7		Sirt3 64384
ENSMUST00000211179 ENSMUSP00000147716	A0A1B0GRY5		Sirt3 64384

More gene data

Top validated antibodies
Invitrogen Antibodies	PA5-86035	1 references	Polyclonal	WB ICC IHC FC OA
NSJ Bioreagents	V9646		Monoclonal	WB EL ICC FC PA OA
LSBio	LS-C346370		Polyclonal	WB ICC IHC
Novus Biologicals	NBP2-52563		Monoclonal	WB EL ICC IHC FC
GeneTex	GTX106292	1 references	Polyclonal	WB ICC IHC

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821 antibodies from 48 providers.

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	Antibody	Refs	Type
Invitrogen Antibodies 30 antibodies
	PA5-86035	1	Polyclonal
	23410-MSM1-P0		Monoclonal

NSJ Bioreagents 7 antibodies
	V9646		Monoclonal
	F49519		Polyclonal

LSBio 136 antibodies
	LS-C346370		Polyclonal
	LS-C379892		Polyclonal

Novus Biologicals 11 antibodies
	NBP2-52563		Monoclonal
	NBP1-31029	1	Polyclonal

GeneTex 6 antibodies
	GTX106292	1	Polyclonal
	GTX115701	1	Polyclonal

Antibodies.com 15 antibodies
	A277615		Monoclonal
	A278203		Monoclonal

antibodies-online 287 antibodies
	ABIN2840669	11	Polyclonal
	ABIN4881048		Monoclonal

Atlas Antibodies 1 antibody
	HPA026809	1	Polyclonal

Proteintech Group 1 antibody
	10099-1-AP	111	Polyclonal

St John's Laboratory 7 antibodies
	STJ72597		Polyclonal
	STJ29446		Polyclonal

Abcepta 8 antibodies
	AP6242a	7	Polyclonal
	AP6242b	1	Polyclonal

Everest Biotech 2 antibodies
	EB10970		Polyclonal
	EB06973		Polyclonal

Biorbyt 48 antibodies
	orb1249278		Polyclonal
	orb2635078		Monoclonal

Affinity Biosciences 2 antibodies
	AF5135		Polyclonal
	DF4684		Polyclonal

FineTest Biotech 1 antibody
	FNab07881		Polyclonal

HUABIO Research 1 antibody
	R1511-3		Polyclonal

Enzo Life Sciences 1 antibody
	BML-SA463-0100		Polyclonal

Cusabio Biotech Co., Ltd 10 antibodies
	CSB-PA882102ESR1HU		Polyclonal
	CSB-PA882102ESR2HU		Polyclonal

Cell Signaling Technology, Inc 2 antibodies
	2627		Monoclonal
	5490		Monoclonal

OriGene 11 antibodies
	AP13216PU-N		Polyclonal
	TA323422		Polyclonal

Abnova Corporation 9 antibodies
	H00023410-M09		Monoclonal
	PAB6891	1	Polyclonal

Boster Biological Technology 2 antibodies
	PB9161	1	Polyclonal
	A01061		Polyclonal

Aviva Systems Biology 8 antibodies
	ARP32389_P050		Polyclonal
	OAAF04538		Polyclonal

Acris Antibodies GmbH 9 antibodies
	AP13216PU-N		Polyclonal
	AP26217PU-N		Polyclonal

FabGennix 3 antibodies
	SIR3-301AP		Polyclonal
	SIR3-BIOTIN		Polyclonal

Bioworld Technology, Inc 1 antibody
	BS7772		Polyclonal

ProSci 7 antibodies
	27-579		Polyclonal
	62-194		Polyclonal

Bioss 12 antibodies
	bs-6105R		Polyclonal
	bs-6105R-Biotin		Polyclonal

NovoPro Bioscience Inc. 1 antibody
	115244		Polyclonal

Creative Biolabs 23 antibodies
	CBMAB-S0279-CQ		Recombinant
	MRO-2189-CN		Polyclonal

Arigo 2 antibodies
	ARG54659		Polyclonal
	ARG63826		Polyclonal

Abbexa 23 antibodies
	abx224373		Monoclonal
	abx005514		Polyclonal

SignalChem 1 antibody
	S37-463R		Polyclonal

Leading Biology 9 antibodies
	APR09953G		Monoclonal
	APR09954G		Monoclonal

R&D Systems 2 antibodies
	AF7488		Polyclonal
	MAB7488		Monoclonal

RabMAbs 3 antibodies
	2860-1		Monoclonal
	S0377		Polyclonal

MyBioSource 7 antibodies
	MBS270394		Polyclonal
	MBS9210535		Polyclonal

Abiocode, Inc. 1 antibody
	R2354-2		Polyclonal

EMD Millipore 1 antibody
	07-1596		Polyclonal

United States Biological 89 antibodies
	041759-AP		Polyclonal
	041759-APC		Polyclonal

MilliporeSigma / Merck KGaA 8 antibodies
	SAB1403135		Monoclonal
	AV32388		Polyclonal

Abbiotec 1 antibody
	254288		Polyclonal

Abbkine Scientific Co.Ltd. 1 antibody
	ABP54341		Polyclonal

GenWay 3 antibodies
	18-003-42198		Polyclonal
	18-003-42199		Polyclonal

RayBiotech, Inc. 1 antibody
	168-10182		Polyclonal

Creative Diagnostics 5 antibodies
	CABT-L1592		Monoclonal
	DPAB-L21121		Polyclonal

MedChemExpress LLC 1 antibody
	HY-P80892		Monoclonal

Rockland Immunochemicals, Inc. 1 antibody
	200-901-EL8		Polyclonal

SIRT3

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SIRT3

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