Tissue expression
Cell line expression
Protein structure
CX3CL1
C-X3-C motif chemokine ligand 1ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1
This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
Top validated antibodies |
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Invitrogen Antibodies | PA5-23062 | 3 references | Polyclonal |
WB
ICC
IHC
OA |
|
R&D Systems | AF537 | 5 references | Polyclonal |
WB
EL
IHC
BN |
|
Novus Biologicals | AF365 | 21 references | Polyclonal |
WB
IHC
BN
|
|
Proteintech Group | 10108-2-AP | 6 references | Polyclonal |
WB
EL
IHC
|
|
antibodies-online | ABIN728488 | 1 references | Polyclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
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Recommended by provider