SPTA1

gene product
EL2
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008]
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153 antibodies from 26 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
NSJ Bioreagents
7 antibodies
GeneTex
7 antibodies
antibodies-online
41 antibodies
Novus Biologicals
5 antibodies
Invitrogen Antibodies
1 antibody
Boster Biological Technology
2 antibodies
Abnova Corporation
3 antibodies
LifeSpan BioSciences, Inc.
16 antibodies
Biorbyt
15 antibodies
Creative Biolabs
15 antibodies
Acris Antibodies GmbH
3 antibodies
OriGene
4 antibodies
Atlas Antibodies
2 antibodies
Aviva Systems Biology
1 antibody
BioLegend (formerly Covance Antibody Products)
1 antibody
BioLegend
2 antibodies
RabMAbs
2 antibodies
St John's Laboratory
1 antibody
MyBioSource
4 antibodies
GenWay
3 antibodies
Creative Diagnostics
2 antibodies
Abbiotec
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Sigma-Aldrich
1 antibody
United States Biological
1 antibody