DAAM1

gene product
KIAA0666
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012]
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338 antibodies from 27 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
6 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
antibodies-online
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Abnova Corporation
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Biorbyt
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Invitrogen Antibodies
4 antibodies
Aviva Systems Biology
4 antibodies
LifeSpan BioSciences, Inc.
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ProSci
4 antibodies
OriGene
4 antibodies
Acris Antibodies GmbH
7 antibodies
Abgent
2 antibodies
Atlas Antibodies
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
RabMAbs
2 antibodies
MyBioSource
6 antibodies
ABEOMICS Inc.
2 antibodies
GeneTex
2 antibodies
United States Biological
51 antibodies
St John's Laboratory
2 antibodies
Creative Biolabs
4 antibodies
Boster Biological Technology
1 antibody
Creative Diagnostics
3 antibodies
Sigma-Aldrich
3 antibodies