CCL19

This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]

Description

chemokine (C-C motif) ligand 19

Protein family

Cancer-related genes, Mapped to UniProt SWISS-PROT, Predicted secreted proteins, Protein evidence (Ezkurdia et al 2014)

Chromosome

9:p13.3 (34689567 - 34691277)

Ensembl ID

ENSG00000172724  (ver. 84.38)

Orthologs

-

UniProt

Q99731

neXtProt

NX_Q99731

Human splice variants