EIF2AK1

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Description

eukaryotic translation initiation factor 2 alpha kinase 1

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted secreted proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

7:p22.1 (6022244 - 6059230)

Ensembl ID

ENSG00000086232  (ver. 84.38)

Orthologs

Mouse Eif2ak1: ENSMUSG00000029613

UniProt

Q9BQI3

neXtProt

NX_Q9BQI3

Human splice variants
Mouse splice variants